Antithrombotic medication use and dementia incidence among mild cognitive
impairment patients with atrial fibrillation
 
   Lead Investigator:    Dana Meranus
   Institution      :    NACC
   E-Mail           :    danahilary@gmail.com
   Proposal ID      :    272


   Publications:


1  Meranus D, Kukull W
   Antithrombotic medication use and dementia incidence in a longitudinal cohort with mild cognitive impairment and atrial fibrillation
   Abstract  Alzheimers Dement,9:P612,2013,

   PUBLISHED





   Proposal Description:
   Aims:  AF may be an independent risk factor for dementia. In the absence of an established cause for higher dementia incidence among patients diagnosed with AF, the role of antithrombotic medications, including both anticoagulants and antiplatelets, will be investigated.                                               Specific Aims:                                                                    (1) Assess if antithrombotic medication use is associated with dementia incidence among patients with mild cognitive impairment who have atrial  fibrillation, and no documented stroke or TIA.                                    (2) Determine if anticoagulant medication, an antithrombotic agent, elevates the risk of dementia incidence.